I did some searches and did not seem to find anything relevant relevant, so here goes.
I installed 13 over a clean, patched MVP installation. Everything worked fine for the first 9 games into my Season with the Reds. Just in case, I created both a save file and a back-up for the save file. However, I am now on my 10th game and the load bar goes all the way during the loading screen before playing the next game and it CTD's. I have tried this with both the reg save and the back-up save. I have also tried simming past that particular game, as well as simming past the entire series with the Pirates, to the same result. Nothing has changed on a hardware / software end. As a matter of fact, I played the ninth game last night before going to bed. I am running Win 7 with quad core, 8 gigs ram, and an ATI 5850 graphics card. Happy to provide any other info that might make troubleshooting easier. I will also update this if I find a fix in the meantime by tinkering around. Any help is greatly appreciated, as I am really loving this mod. If I over-looked anything that would contain my answer, I apologize in advance.
Edit: And just for clarity sake, the error message that I get is mvp2005.exe has stopped working. I have also tried to run the game in every compatibility mode available, with no love. I also tried just starting a new season to see what happens. I ctd on game 1 in the same way.