Only took you 3 posts to tell me what info to give you. That could have been the first thing you asked me.
What OS are you running? Windows 7 premium
Have you installed any hardware or software on the PC since the last time you played MVP without a crash? No
How long ago was it that the game actually worked for you? Yesterday
How much free hard drive space do you have? ~7gb
When was the last time you used your MVP CD's? Today
Could disc 2 (which is required to play the game) have gotten scratched? Nope